⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1995080 | 0.76 | CCND1 (0.37) | — | |
| SCHEMBL25857099 | 0.76 | HCAR1 (0.31) | — | |
| SCHEMBL4200625 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL28174161 | 0.75 | — | — | |
| SCHEMBL28227350 | 0.75 | — | — | |
| SCHEMBL24052556 | 0.74 | — | — | |
| SCHEMBL28294705 | 0.74 | CCNB2 (0.31) | — | |
| SCHEMBL29651155 | 0.73 | MAT2A (0.33) | — | |
| SCHEMBL24267967 | 0.73 | — | — | |
| SCHEMBL28175196 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308654-B2 | Preparation and use of kinase inhibitor | CHANGZHOU LONGTHERA PHARMACEUTICALS INC. (CN) | 2019-06-04 | — | — | US | disclosed |
| US-20180127419-A1 | PREPARATION AND USE OF KINASE INHIBITOR | CHANGZHOU LONGTHERA PHAMACEUTICALS INC (CN) | 2018-05-10 | — | — | US | disclosed |
| US-20180127419-A1 | PREPARATION AND USE OF KINASE INHIBITOR | CHANGZHOU LONGTHERA PHAMACEUTICALS INC (CN) | 2018-05-10 | — | — | US | disclosed |