Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCND2 | P30279 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4200629 | 0.99 | CCNB2 (0.32) | CCNB2CCNE2CDK1FGFR1CDK4 | |
| SCHEMBL19336275 | 0.80 | STK17B (0.47) | — | |
| SCHEMBL30292479 | 0.77 | DCTPP1 (0.40) | CCNE2CCNE1CDK2 | |
| SCHEMBL4196176 | 0.77 | ENPP2 (0.39) | ENPP2HSP90B1PDE4B | |
| SCHEMBL4200625 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL4201281 | 0.74 | CCR9 (0.39) | CCNB2CCNE2CDK1FGFR1CDK4 | |
| SCHEMBL20127004 | 0.74 | — | — | |
| SCHEMBL30661265 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL19301812 | 0.73 | STK17B (0.34) | — | |
| SCHEMBL29651155 | 0.73 | MAT2A (0.33) | CDK4CCND1CCND2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789143-A | Antiproliferative based on pyrimidine | G1治疗公司 | 2019-05-21 | — | — | CN | disclosed |