SCHEMBL20127440

SCHEMBL20127440

CC1(C)c2cc(-c3c4ccccc4c(-c4c5ccccc5cc5c4oc4ccccc45)c4ccccc34)ccc2-c2c1ccc1ccccc21

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.32
PGR P06401 1/20 0.32
AHR P35869 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127645 0.95 PGR (0.32) ALOX5PGRAHRMEN1ALDH1A1
SCHEMBL20127408 0.89 ALOX5 (0.34) ALOX5PGRAHRMEN1ALDH1A1
SCHEMBL17944095 0.89 ALOX5 (0.35) ALOX5PGRAHR
SCHEMBL19107946 0.88 ALOX5 (0.36) ALOX5PGRMEN1KMT2A
SCHEMBL24285544 0.87 ALOX5 (0.41) ALOX5PGRMEN1ALDH1A1KMT2A
SCHEMBL20127620 0.87 ALOX5 (0.34) ALOX5PGRMEN1ALDH1A1KMT2A
SCHEMBL10122596 0.87 GPR84 (0.36) ALOX5PGRAHR
SCHEMBL24285507 0.87 AHR (0.35) ALOX5PGRAHRMEN1ALDH1A1
SCHEMBL17944370 0.87 HSP90AA1 (0.35) PGRAHRMEN1ALDH1A1KMT2A
SCHEMBL20127676 0.87 L3MBTL1 (0.30) ALOX5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885PGR 1148/4885AHR 2558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.