SCHEMBL20127481

SCHEMBL20127481

CC1(C)c2ccccc2-c2c1cc(-c1c3ccccc3c(-c3ccc4c(ccc5oc6ccccc6c54)c3)c3ccccc13)c1ccccc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CASP3 P42574 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
HCRTR1 O43613 1/20 0.32
ABCG2 Q9UNQ0 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127577 0.91 ABCG2 (0.34) L3MBTL1TDP1ABCG2
SCHEMBL20127304 0.90 ABCG2 (0.35) L3MBTL1TDP1ABCG2
SCHEMBL20127479 0.89 L3MBTL1 (0.34) L3MBTL1TDP1CASP3SENP7SENP6
SCHEMBL24004224 0.86 HSP90AA1 (0.39) L3MBTL1CASP3SENP7SENP6
SCHEMBL17943939 0.86 AHR (0.37) L3MBTL1HCRTR1
SCHEMBL20127486 0.86 CASP3 (0.33) L3MBTL1TDP1CASP3SENP7SENP6
SCHEMBL20127497 0.85 CASP3 (0.33) L3MBTL1TDP1CASP3SENP7SENP6
SCHEMBL24397831 0.85 PGR (0.33) L3MBTL1
SCHEMBL20127483 0.84 TDP1 (0.37) L3MBTL1TDP1ABCG2
SCHEMBL24004226 0.82 PGR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 L3MBTL1 1670/4885TDP1 3427/4885CASP3 3455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.