SCHEMBL20127486

SCHEMBL20127486

CC1(C)c2ccccc2-c2ccc(-c3ccc(-c4c5ccccc5c(-c5ccc6c(ccc7oc8ccccc8c76)c5)c5ccccc45)cc3)cc21

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
HCRTR1 O43613 1/20 0.33
PGR P06401 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PDK2 Q15119 2/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127479 0.97 L3MBTL1 (0.34) CASP3SENP7SENP6HCRTR1TDP1
SCHEMBL20127497 0.95 CASP3 (0.33) CASP3SENP7SENP6HCRTR1PGR
SCHEMBL20127585 0.92 ABCG2 (0.34) HCRTR1TDP1L3MBTL1PDK2ABCG2
SCHEMBL20127310 0.90 ABCG2 (0.34) CASP3SENP7SENP6TDP1PDK2
SCHEMBL20127575 0.88 ABCG2 (0.35) TDP1L3MBTL1ABCG2
SCHEMBL19109865 0.88 PGR (0.33) HCRTR1PGR
SCHEMBL19109868 0.88 MAOA (0.34) HCRTR1PGR
SCHEMBL24341716 0.87 ALK (0.31)
SCHEMBL10122702 0.87 ABCG2 (0.34) HCRTR1TDP1L3MBTL1ABCG2
SCHEMBL19109892 0.87 HSP90AA1 (0.33) CASP3SENP7SENP6PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 CASP3 3455/4885SENP7 4802/4885SENP6 4844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.