SCHEMBL20127677

SCHEMBL20127677

c1ccc2c(c1)ccc1cc(-c3c4ccccc4c(-c4cc5c6ccccc6oc5c5c4oc4ccccc45)c4ccccc34)ccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
SOS1 Q07889 1/20 0.38
KDM4E B2RXH2 6/20 0.37
HPGD P15428 5/20 0.37
HSD17B10 Q99714 5/20 0.37
MAPT P10636 5/20 0.37
ALDH1A1 P00352 5/20 0.37
TSHR P16473 3/20 0.37
CASP7 P55210 2/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
ALOX5 P09917 1/20 0.36
GLA P06280 2/20 0.35
HTT P42858 1/20 0.35
CYP1A1 P04798 4/20 0.35
CYP1B1 Q16678 4/20 0.35
KMT2A Q03164 3/20 0.35
MAPK1 P28482 2/20 0.35
AHR P35869 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127668 0.94 KDM4E (0.38) L3MBTL1TDP1SOS1KDM4EHPGD
SCHEMBL10122250 0.92 GPR84 (0.38) L3MBTL1TDP1SOS1KDM4EHPGD
SCHEMBL20127702 0.91 GPR84 (0.37) L3MBTL1TDP1KDM4EHPGDHSD17B10
SCHEMBL10122608 0.89 CYP1A1 (0.43) L3MBTL1TDP1KDM4EHPGDHSD17B10
SCHEMBL17944111 0.89 PGR (0.38) L3MBTL1KDM4EHPGDHSD17B10MAPT
SCHEMBL20127674 0.89 SOS1 (0.47) L3MBTL1TDP1SOS1KDM4EHPGD
SCHEMBL20127395 0.88 ALOX5 (0.41) L3MBTL1TDP1SOS1KDM4EHPGD
SCHEMBL10122231 0.88 ALOX5 (0.37) L3MBTL1TDP1KDM4EHPGDHSD17B10
SCHEMBL19294639 0.88 ALOX5 (0.36) L3MBTL1KDM4EHPGDHSD17B10MAPT
SCHEMBL10122257 0.88 GPR84 (0.36) L3MBTL1TDP1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 L3MBTL1 1670/4885TDP1 3427/4885SOS1 960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.