SCHEMBL20127668

SCHEMBL20127668

c1ccc2c(c1)ccc1ccc(-c3c4ccccc4c(-c4cc5c6ccccc6oc5c5c4oc4ccccc45)c4ccccc34)cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 4/20 0.38
MAPT P10636 4/20 0.38
ALDH1A1 P00352 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
TSHR P16473 2/20 0.38
CASP7 P55210 2/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
ALOX5 P09917 1/20 0.36
GLA P06280 2/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 3/20 0.36
MAPK1 P28482 1/20 0.36
AHR P35869 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
FYN P06241 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127677 0.94 L3MBTL1 (0.40) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL10122250 0.91 GPR84 (0.38) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL20127702 0.90 GPR84 (0.37) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL17932057 0.88 ALOX5 (0.42) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL17944904 0.88 MAPT (0.41) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL20127672 0.88 ALOX5 (0.39) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL17944111 0.87 PGR (0.38) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL19081704 0.87 KDM4E (0.37) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL10122231 0.86 ALOX5 (0.37) KDM4EHSD17B10HPGDMAPTALDH1A1
SCHEMBL24614906 0.86 KDM4E (0.37) KDM4EHSD17B10HPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 KDM4E 4144/4885HSD17B10 2025/4885HPGD 4205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.