Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117827 | 0.81 | ALDH1A1 (0.41) | PKMALDH1A1POLBCTDSP1TDP1 | |
| SCHEMBL25857160 | 0.78 | ALDH1A1 (0.31) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL18120926 | 0.74 | ALDH1A1 (0.44) | PKMALDH1A1POLBCTDSP1TDP1 | |
| SCHEMBL25857181 | 0.72 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL19502410 | 0.68 | ALDH1A1 (0.40) | PKMALDH1A1POLBCTDSP1TDP1 | |
| SCHEMBL18098030 | 0.68 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL18120934 | 0.67 | MAPT (0.44) | PKMSMN1; SMN2ALDH1A1POLBCTDSP1 | |
| SCHEMBL18117828 | 0.66 | ALDH1A1 (0.38) | PKMALDH1A1POLBCTDSP1TDP1 | |
| SCHEMBL17830121 | 0.64 | SMN1; SMN2 (0.49) | PKMSMN1; SMN2ALDH1A1POLBCTDSP1 | |
| SCHEMBL19115781 | 0.63 | ALDH1A1 (0.35) | PKMALDH1A1POLBCTDSP1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180125791-A1 | POLYMER NANOCAPSULES FOR PROTEIN DELIVERY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125791-A1 | POLYMER NANOCAPSULES FOR PROTEIN DELIVERY | HNRNPA1, AUP1, NAP1L1 | PKM 2910/4885SMN1; SMN2 1031/4885ALDH1A1 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.