SCHEMBL25857160

SCHEMBL25857160

C=CC1OC(C=C)C2C(=O)N(CCNC(=N)N)C(=O)C12

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857181 0.85 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TP53
SCHEMBL20128036 0.78 PKM (0.31) ALDH1A1SMN1; SMN2
SCHEMBL22100113 0.77 OPRM1 (0.46) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL18117828 0.76 ALDH1A1 (0.38) ALDH1A1
SCHEMBL25857062 0.73 ALDH1A1 (0.45) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857060 0.73 ALDH1A1 (0.45) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857066 0.73 ALDH1A1 (0.43) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857073 0.72 ALDH1A1 (0.42) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857058 0.72 ALDH1A1 (0.37) ALDH1A1
SCHEMBL25857068 0.72 ALDH1A1 (0.46) ALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885NPC1 1081/4885RAB9A 1420/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885NPC1 1081/4885RAB9A 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.