SCHEMBL25857181

SCHEMBL25857181

C=CC1OC(/C=C\C2OC(C=C)C3C(=O)N(Cc4ccccc4)C(=O)C23)C2C(=O)N(CCNC(=N)N)C(=O)C12

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
F2 P00734 4/20 0.37
TSHR P16473 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 2/20 0.35
HPGD P15428 1/20 0.35
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
HIF1A Q16665 1/20 0.34
USP2 O75604 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EP300 Q09472 1/20 0.33
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857160 0.85 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2TP53
SCHEMBL25857182 0.76 ALDH1A1 (0.42) ALDH1A1KMT2AMAPT
SCHEMBL25857068 0.75 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ATSHRSMN1; SMN2
SCHEMBL25857056 0.75 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ATSHRSMN1; SMN2
SCHEMBL25857050 0.74 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL25857077 0.74 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL15339880 0.73 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ATSHRSMN1; SMN2
SCHEMBL25857060 0.72 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL25857062 0.72 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL25857066 0.72 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885MEN1 2661/4885KMT2A 2590/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885MEN1 2661/4885KMT2A 2590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.