Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL431332 | 0.88 | HIF1A (0.46) | TYMPHIF1APOLBENPP1P2RY1 | |
| SCHEMBL10022902 | 0.88 | HIF1A (0.46) | TYMPHIF1APOLBENPP1P2RY1 | |
| SCHEMBL30821669 | 0.88 | HIF1A (0.46) | TYMPHIF1APOLBENPP1P2RY1 | |
| SCHEMBL887467 | 0.88 | HIF1A (0.46) | TYMPHIF1APOLBENPP1P2RY1 | |
| SCHEMBL20129802 | 0.88 | HIF1A (0.46) | TYMPHIF1APOLBENPP1P2RY1 | |
| SCHEMBL22598549 | 0.88 | METTL3 (0.39) | TYMPHIF1A | |
| SCHEMBL26068422 | 0.88 | METTL3 (0.39) | TYMPHIF1A | |
| SCHEMBL2611648 | 0.86 | ADK (0.38) | TYMP | |
| SCHEMBL20810884 | 0.86 | ADK (0.38) | TYMP | |
| SCHEMBL22327400 | 0.85 | TYMP (0.30) | TYMPHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203083-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | TYMP 5/4885HIF1A 2056/4885POLB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.