SCHEMBL20130866

SCHEMBL20130866

CSO[SiH](C)N(C)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.38
PHGDH O43175 1/20 0.38
MGLL Q99685 1/20 0.38
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 2/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
METAP2 P50579 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985068 0.73 HTT (0.35) FAAHPHGDHMGLLMEN1HTT
SCHEMBL3130771 0.68 MEN1 (0.46) FAAHPHGDHMGLLMEN1HTT
SCHEMBL18378161 0.68 MEN1 (0.46) FAAHPHGDHMGLLMEN1HTT
SCHEMBL15135243 0.67 MEN1 (0.41) FAAHPHGDHMGLLMEN1HTT
SCHEMBL10393863 0.63 ALDH1A1 (0.56) MEN1HTTKMT2ATDP1L3MBTL1
Methylsulfanylmethane SCHEMBL27495758 0.63 ALDH1A1 (0.56) FAAHPHGDHMGLLMEN1HTT
SCHEMBL25717553 0.63 CA4 (0.31)
SCHEMBL15135156 0.61 KMT2A (0.38) FAAHPHGDHMGLLMEN1HTT
SCHEMBL236025 0.61 LMNA (0.42) FAAHPHGDHMGLLMEN1HTT
SCHEMBL20385081 0.59 MEN1 (0.52) FAAHPHGDHMGLLMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703915-B2 Compositions and methods for the deposition of silicon oxide films VERSUM MATERIALS US, LLC (US) 2020-07-07 US disclosed
US-20200040192-A9 Compositions and Methods for the Deposition of Silicon Oxide Films VERSUM MATERIALS US, LLC (US) 2020-02-06 US disclosed
US-20180127592-A1 Compositions and Methods for the Deposition of Silicon Oxide Films VERSUM MATERIALS US, LLC (US) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180127592-A1 Compositions and Methods for the Deposition of Silicon Oxide Films SEPTIN9, SGMS1, SGMS2 FAAH 4734/4885PHGDH 3485/4885MGLL 2157/4885
US-20200040192-A9 Compositions and Methods for the Deposition of Silicon Oxide Films SEPTIN9, SGMS1, SGMS2 FAAH 4734/4885PHGDH 3485/4885MGLL 2157/4885
US-10703915-B2 Compositions and methods for the deposition of silicon oxide films SEPTIN9, SGMS1, SGMS2 FAAH 4734/4885PHGDH 3485/4885MGLL 2157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.