Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034061 | 0.83 | P2RX7 (0.36) | ALDH1A1MAPTCHRM1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2014478 | 0.83 | P2RX7 (0.36) | ALDH1A1MAPTCHRM1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2012604 | 0.79 | FKBP1A (0.32) | ALDH1A1NPC1RAB9AMAPTFKBP1A | |
| SCHEMBL2016437 | 0.73 | MAPT (0.52) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2014101 | 0.73 | MAPT (0.52) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2014401 | 0.68 | BCHE (0.38) | ALDH1A1MAPTPOLBMEN1LMNA | |
| SCHEMBL2038718 | 0.68 | LMNA (0.33) | KDM4ETDP1ALDH1A1NPC1RAB9A | |
| SCHEMBL22499927 | 0.64 | EPHX2 (0.40) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL22499881 | 0.64 | EPHX2 (0.41) | ALDH1A1NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL18978629 | 0.63 | PRKCD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513069-A1 | ANTIFUNGAL COMPOUNDS | Katholieke Universiteit Leuven (BE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072345-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2011-06-23 | — | — | WO | disclosed |