Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012604 | 0.86 | FKBP1A (0.32) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL2038718 | 0.80 | LMNA (0.33) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL2015469 | 0.75 | RAB9A (0.47) | BCHEACHEFAAHPKMMAOB | |
| SCHEMBL2012481 | 0.71 | GAA (0.40) | ALDH1A1GRM6MAPTAMPD2POLB | |
| SCHEMBL2034061 | 0.71 | P2RX7 (0.36) | BCHEPKMMAOBALDH1A1MAPT | |
| SCHEMBL2013111 | 0.68 | KDM4E (0.35) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL2012819 | 0.68 | HTT (0.36) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL13369775 | 0.67 | NPC1 (0.35) | FAAHPKMALDH1A1MAPTLMNA | |
| SCHEMBL2012480 | 0.65 | PLA2G10 (0.39) | ALDH1A1GRM6MAPTKMT2A | |
| SCHEMBL2013756 | 0.63 | MAPT (0.46) | ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513069-A1 | ANTIFUNGAL COMPOUNDS | Katholieke Universiteit Leuven (BE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072345-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2011-06-23 | — | — | WO | disclosed |