Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014401 | 0.86 | BCHE (0.38) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL2038718 | 0.85 | LMNA (0.33) | FKBP1APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL2016596 | 0.82 | SMN1; SMN2 (0.33) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2013111 | 0.79 | KDM4E (0.35) | FKBP1APOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL2014478 | 0.75 | P2RX7 (0.36) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2034061 | 0.75 | P2RX7 (0.36) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2014822 | 0.75 | CACNA1F (0.31) | — | |
| SCHEMBL13369775 | 0.73 | NPC1 (0.35) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2011806 | 0.73 | MAPT (0.53) | POLBKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2012384 | 0.72 | SIRT2 (0.36) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513069-A1 | ANTIFUNGAL COMPOUNDS | Katholieke Universiteit Leuven (BE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072345-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2011-06-23 | — | — | WO | disclosed |