Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6297863 | 0.78 | L3MBTL1 (0.54) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6304504 | 0.77 | KDM4E (0.55) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 | |
| SCHEMBL17749098 | 0.76 | PKM (0.53) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 | |
| SCHEMBL20133962 | 0.76 | TRPM5 (0.50) | PTPN1PTPN11GAACYP2C19ALOX12 | |
| SCHEMBL6297762 | 0.74 | L3MBTL1 (0.52) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 | |
| SCHEMBL456924 | 0.74 | L3MBTL1 (0.69) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 | |
| SCHEMBL1417373 | 0.73 | L3MBTL1 (0.54) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6298739 | 0.73 | L3MBTL1 (0.51) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6298735 | 0.72 | L3MBTL1 (0.67) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL456056 | 0.72 | KDM4E (0.55) | L3MBTL1PTPN1PTPN11KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | HRH4, H1-10, HDAC10 | L3MBTL1 1531/4885PTPN1 1619/4885PTPN11 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.