Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17749206 | 0.77 | TRPM5 (0.48) | TRPM5CYP2C19DNMT1GAA | |
| SCHEMBL20133924 | 0.76 | L3MBTL1 (0.50) | CYP2C19ALOX12PTPN11PTPN1GAA | |
| SCHEMBL6297758 | 0.75 | CYP2C19 (0.57) | TRPM5CYP2C19MAP3K8KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL6297635 | 0.74 | CYP2C19 (0.56) | TRPM5CYP2C19MAP3K8KDM1AMAOB | |
| SCHEMBL5692948 | 0.73 | TRPM5 (0.52) | TRPM5CYP2C19MAP3K8KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL5850699 | 0.72 | TRPM5 (0.51) | TRPM5CYP2C19MAP3K8KDM1AMAOB | |
| SCHEMBL7953745 | 0.70 | LOXL2 (0.51) | TRPM5CYP2C19MAP3K8KDM1AMAOB | |
| SCHEMBL17761391 | 0.69 | KCNQ2 (0.62) | TRPM5CYP2C19PTGS2 | |
| SCHEMBL2718512 | 0.69 | MAOB (0.55) | TRPM5CYP2C19KDM1AMAOBTLR7 | |
| SCHEMBL28866138 | 0.68 | ALDH1A1 (0.36) | CYP2C19GAAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | HRH4, H1-10, HDAC10 | TRPM5 3215/4885CYP2C19 739/4885MAP3K8 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.