Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135492 | 0.91 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AHTTENPP2 | |
| SCHEMBL29813610 | 0.83 | GFER (0.63) | SMN1; SMN2RAB9AMAPTCYP2C9CYP3A4 | |
| SCHEMBL21206785 | 0.83 | GFER (0.63) | SMN1; SMN2RAB9AMAPTCYP2C9CYP3A4 | |
| SCHEMBL5347264 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AHTTENPP2 | |
| SCHEMBL4509567 | 0.79 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AHTTENPP2 | |
| SCHEMBL25237507 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AHTTENPP2 | |
| SCHEMBL11750711 | 0.77 | ENPP2 (0.78) | SMN1; SMN2NPC1RAB9AHTTENPP2 | |
| SCHEMBL1554384 | 0.77 | GRIN2B (0.71) | SMN1; SMN2NPC1RAB9AHTTENPP2 | |
| SCHEMBL3533651 | 0.76 | SMN1; SMN2 (0.77) | SMN1; SMN2NPC1RAB9AHTTENPP2 | |
| SCHEMBL5352840 | 0.76 | GRIN2B (0.60) | SMN1; SMN2NPC1RAB9AHTTENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP1 | SMN1; SMN2 2532/4885NPC1 4881/4885RAB9A 270/4885 |
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MMP9, MMP2, MMP1 | SMN1; SMN2 2476/4885NPC1 4882/4885RAB9A 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.