SCHEMBL20135773

SCHEMBL20135773

C/C=C\c1ccccc1OC1(Oc2ccccc2/C=C\C)C=CC(C(=O)c2ccccc2)C=C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.41
MAPT P10636 3/20 0.41
RAB9A P51151 2/20 0.41
LMNA P02545 2/20 0.41
BCHE P06276 1/20 0.41
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 1/20 0.37
GAA P10253 1/20 0.36
NFE2L2 Q16236 2/20 0.35
TFEB P19484 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 2/20 0.35
NR1H4 Q96RI1 1/20 0.34
CYP1A2 P05177 3/20 0.33
CYP2D6 P10635 3/20 0.33
MAOB P27338 2/20 0.33
CYP1A1 P04798 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP1B1 Q16678 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8911079 0.76 HTT (0.36) MAPTLMNAHTTGAASMN1; SMN2
SCHEMBL6537068 0.74 AKR1C3 (0.37) MAPTKMT2AHTTKDM4EHPGD
SCHEMBL210844 0.74 TSHR (0.41) MAPTLMNAKMT2AMEN1HTT
SCHEMBL10893912 0.73 TDP1 (0.42) NPC1MAPTRAB9AKMT2AMEN1
SCHEMBL10586101 0.72 ELANE (0.38) NPC1MAPTLMNAKMT2AHTT
SCHEMBL1627984 0.70 MAOA (0.36) NPC1MAPTRAB9ALMNAKMT2A
SCHEMBL9750703 0.70 PBRM1 (0.42) NPC1MAPTRAB9ALMNAKMT2A
SCHEMBL5267430 0.70 POLB (0.48) LMNAHTTKDM4ECYP1A2CYP2D6
Ammonia Solution, Strong SCHEMBL10582921 0.69 MAOA (0.35) NPC1MAPTRAB9ALMNAKMT2A
SCHEMBL2470208 0.69 EPHX1 (0.43) NPC1MAPTKMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3321319-B1 RESIN COMPOSITION AND PREPREG, RESIN SHEET, LAMINATE PLATE, AND PRINTED CIRCUIT BOARD MITSUBISHI GAS CHEMICAL CO (JP) 2022-10-05 EP disclosed
US-10563029-B2 Resin composition and prepreg, resin sheet, laminate, and printed circuit board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-02-18 US disclosed
US-20180186952-A1 RESIN COMPOSITION AND PREPREG, RESIN SHEET, LAMINATE, AND PRINTED CIRCUIT BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-07-05 US disclosed
EP-3321319-A1 RESIN COMPOSITION, PREPREG, RESIN SHEET, LAMINATE PLATE, AND PRINTED WIRING BOARD Mitsubishi Gas Chemical Company, Inc. (JP) 2018-05-16 EP disclosed