Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649899 | 0.90 | POLB (0.39) | AKR1C3ALDH1A1HSD17B10TDP1POLB | |
| SCHEMBL8911079 | 0.76 | HTT (0.36) | AKR1C3ALDH1A1HSD17B10TSHRNAPRT | |
| SCHEMBL5267430 | 0.75 | POLB (0.48) | AKR1C3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL20135773 | 0.74 | NPC1 (0.41) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL4675279 | 0.73 | PYGL (0.36) | AKR1C3ALDH1A1HSD17B10TDP1POLB | |
| SCHEMBL210844 | 0.71 | TSHR (0.41) | ALDH1A1HPGDHSD17B10TSHRNAPRT | |
| SCHEMBL1627984 | 0.70 | MAOA (0.36) | MAPTHTTELANEKMT2AALOX15 | |
| SCHEMBL9750703 | 0.70 | PBRM1 (0.42) | AKR1C3ALDH1A1POLBMAPTKMT2A | |
| Ammonia Solution, Strong SCHEMBL10582921 | 0.69 | MAOA (0.35) | MAPTHTTELANEKMT2AALOX15 | |
| SCHEMBL156512 | 0.69 | MAPT (0.40) | AKR1C3ALDH1A1HSD17B10TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673872-B2 | BLEND OF POLYIMIDE THERMOPLASTIC AND LOW VISCOSITY POLY(ARYLENE) ETHER | GENERAL ELECTRIC COMPANY | 2004-01-06 | — | — | US | claimed |
| US-20030125478-A1 | HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2003-07-03 | — | — | US | claimed |
| EP-0900828-A1 | Polyetherimide resin/polyester resin blends | GENERAL ELECTRIC COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| EP-0315025-A1 | Amide-imide copolymers and process for the preparation thereof | GENERAL ELECTRIC COMPANY (US) | 1989-05-10 | — | — | EP | disclosed |