Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969139 | 0.81 | HTR1A (0.48) | HTR1APDE3BPDE3ACYP3A4CYP19A1 | |
| SCHEMBL3309120 | 0.77 | BRD4 (0.45) | CYP3A4MAPK1CYP19A1MAOB | |
| SCHEMBL7196340 | 0.75 | SNCA (0.46) | PDE3BPDE3ACYP3A4MAPK1CYP19A1 | |
| SCHEMBL3358045 | 0.74 | ALDH1A1 (0.45) | HTR1ALMNA | |
| SCHEMBL5508843 | 0.74 | ALOX15 (0.50) | HTR1ACYP3A4MAPK1CYP19A1MAOB | |
| SCHEMBL31435210 | 0.72 | ALDH1A1 (0.49) | PDE3BPDE3AMAOBSNCAHTR2C | |
| SCHEMBL4233305 | 0.72 | ALDH1A1 (0.49) | PDE3BPDE3AMAOBSNCAHTR2C | |
| Hydrochloric Acid SCHEMBL1851740 | 0.71 | ALDH1A1 (0.47) | PDE3BPDE3ACYP3A4MAOBSNCA | |
| SCHEMBL914279 | 0.71 | CA2 (0.46) | PDE3BPDE3ACYP3A4MAPK1CYP19A1 | |
| SCHEMBL30060716 | 0.71 | CA2 (0.46) | PDE3BPDE3ACYP3A4MAPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |