Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435210 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GAAHSD17B10MAPTAURKA | |
| Hydrochloric Acid SCHEMBL1851740 | 0.98 | ALDH1A1 (0.47) | ALDH1A1GAAHSD17B10MAPTAURKA | |
| SCHEMBL31371763 | 0.90 | ALDH1A1 (0.39) | ALDH1A1GAAHSD17B10MAPTAURKA | |
| SCHEMBL4233291 | 0.90 | ALDH1A1 (0.39) | ALDH1A1GAAHSD17B10MAPTAURKA | |
| SCHEMBL1513451 | 0.86 | ALDH1A1 (0.62) | ALDH1A1GAAHSD17B10MAPTPDE3B | |
| SCHEMBL31452931 | 0.86 | ALDH1A1 (0.62) | ALDH1A1GAAHSD17B10MAPTPDE3B | |
| SCHEMBL7196340 | 0.82 | SNCA (0.46) | ALDH1A1GAAHSD17B10MAPTPDE3B | |
| SCHEMBL19231667 | 0.82 | ALDH1A1 (0.45) | ALDH1A1GAAHSD17B10MAPTAURKA | |
| SCHEMBL5667298 | 0.80 | CA2 (0.44) | ALDH1A1GAAHSD17B10MAPTAURKA | |
| SCHEMBL23153424 | 0.79 | HTR1A (0.41) | ALDH1A1GAAHSD17B10MAPTAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025091026-A1 | THERAPEUTIC COMPOSITIONS CONTAINING G-CLAMP PNA AND USES THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2025-05-01 | — | — | WO | claimed |
| WO-2025091026-A1 | THERAPEUTIC COMPOSITIONS CONTAINING G-CLAMP PNA AND USES THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2025-05-01 | — | — | WO | disclosed |
| WO-2025041625-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-02-27 | — | — | WO | disclosed |
| WO-2025036382-A1 | SULFONAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海复宏汉霖生物医药有限公司 | 2025-02-20 | — | — | WO | disclosed |
| US-11912708-B2 | Macrocyclic heterocycles and uses thereof | KUMQUAT BIOSCIENCES INC. (US) | 2024-02-27 | — | — | US | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
| EP-4125861-A2 | PROTEIN-PROTEIN INTERACTION STABILIZERS | The Regents of the University of California (US) | 2023-02-08 | — | — | EP | disclosed |
| US-20230028644-A1 | Low Greenhouse Gas Fuel Compositions | BP OIL INTERNATIONAL LIMITED (GB) | 2023-01-26 | — | — | US | disclosed |
| US-20220402925-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | FLATLEY DISCOVERY LAB LLC (US) | 2022-12-22 | — | — | US | disclosed |
| US-20070155740-A1 | SUBSTITUTED PYRAZINONES, PYRIDINES AND PYRIMIDINES AS CORTICOTROPIN RELEASING FACTOR LIGANDS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-07-05 | — | — | US | disclosed |
| US-7205306-B2 | Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1392309-B1 | SUBSTITUTED PYRAZINONES, PYRIDINES AND PYRIMIDINES AS CORTICOTROPIN RELEASING FACTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2007-01-17 | — | — | EP | disclosed |
| US-20070010670-A1 | Nitrogen-containing fused ring compounds and use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-11 | — | — | US | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
| US-20030171380-A1 | Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands | BRISTOL-MYERS SQUIBB PHARMA COMPANY, (FORMERLY D/B/A DUPONT PHARMACEUTICALS COMPANY) | 2003-09-11 | — | — | US | disclosed |
| EP-0592396-B1 | BENZOXAZINE DYES | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5118323-A | Hair dyes | CLAIROL, INC. | 1992-06-02 | — | — | US | disclosed |
| US-5055110-A | Hair dyes | CLAIROL INCORPORATED (US) | 1991-10-08 | — | — | US | disclosed |
| US-4288589-A | Cationic dyes | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912708-B2 | Macrocyclic heterocycles and uses thereof | HRAS, KRAS, TP53 | ALDH1A1 4341/4885GAA 4116/4885HSD17B10 3312/4885 |
| US-20030171380-A1 | Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands | CRH, CRHR1, CRHR2 | ALDH1A1 2333/4885GAA 4390/4885HSD17B10 2411/4885 |
| US-20220402925-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, ABCB11, SERPINB1 | ALDH1A1 814/4885GAA 90/4885HSD17B10 550/4885 |
| US-20070155740-A1 | SUBSTITUTED PYRAZINONES, PYRIDINES AND PYRIMIDINES AS CORTICOTROPIN RELEASING FACTOR LIGANDS | CRH, CRHR1, CRHR2 | ALDH1A1 2429/4885GAA 4436/4885HSD17B10 2431/4885 |
| US-20070010670-A1 | Nitrogen-containing fused ring compounds and use thereof | NUDT1, NOD1, SLC28A1 | ALDH1A1 605/4885GAA 3626/4885HSD17B10 633/4885 |
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | ALDH1A1 3889/4885GAA 3615/4885HSD17B10 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.