Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140477 | 0.87 | HTR7 (0.58) | HTR7ALDH1A1KDM4ENPY2RDRD4 | |
| SCHEMBL20159024 | 0.81 | MTOR (0.64) | HTR7MEN1KMT2ADRD2POLB | |
| SCHEMBL20159036 | 0.79 | MTOR (0.58) | HTR7KDM4EDRD4DRD2DRD3 | |
| SCHEMBL20159115 | 0.78 | MTOR (0.55) | HTR7USP2LMNAMAPTPOLB | |
| SCHEMBL20159119 | 0.77 | HTR7 (0.54) | HTR7ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL20159079 | 0.77 | MTOR (0.52) | HTR7LMNADRD2POLBMTOR | |
| SCHEMBL20159144 | 0.77 | KDM4E (0.50) | HTR7ALDH1A1KDM4ELMNANPY2R | |
| SCHEMBL20139324 | 0.76 | MTOR (0.52) | HTR7NPY2RMTORRPTORMLST8 | |
| SCHEMBL20139564 | 0.76 | MTOR (0.52) | HTR7NPY2RMTORRPTORMLST8 | |
| SCHEMBL20159286 | 0.76 | MTOR (0.51) | HTR7LMNAPOLBMTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |