Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140477 | 0.80 | HTR7 (0.58) | KDM4EDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL20139284 | 0.77 | HTR7 (0.52) | KDM4EDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL6864941 | 0.75 | DRD4 (0.81) | KDM4EDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL20159024 | 0.74 | MTOR (0.64) | DRD2HTR7HTR1A | |
| SCHEMBL260265 | 0.73 | HRH3 (0.49) | KDM4EALDH1A1LMNA | |
| SCHEMBL7426690 | 0.73 | DRD4 (0.68) | KDM4EDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL6029899 | 0.72 | SIGMAR1 (0.68) | KDM4EDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL20159036 | 0.71 | MTOR (0.58) | KDM4EDRD2DRD4DRD3HTR7 | |
| SCHEMBL6865213 | 0.71 | ALDH1A1 (0.67) | KDM4EDRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL20159079 | 0.70 | MTOR (0.52) | DRD2HTR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |