Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139604 | 0.81 | HDAC4 (0.40) | HDAC4SLC6A9 | |
| SCHEMBL20139680 | 0.76 | HDAC4 (0.39) | HDAC4 | |
| SCHEMBL21229255 | 0.72 | MAPK9 (0.37) | — | |
| SCHEMBL17316873 | 0.70 | HDAC4 (0.49) | HDAC4SLC6A9 | |
| SCHEMBL20141623 | 0.69 | HDAC4 (0.37) | HDAC4SLC6A9 | |
| SCHEMBL5071497 | 0.62 | NFE2L2 (0.38) | HDAC4 | |
| SCHEMBL7640862 | 0.61 | KDM4E (0.39) | SLC6A9 | |
| SCHEMBL31092428 | 0.60 | — | — | |
| SCHEMBL4269628 | 0.60 | — | — | |
| SCHEMBL3293490 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538520-A2 | SGC STIMULATORS | Cyclerion Therapeutics, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089330-A2 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |