Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MTOR | P42345 | 4/20 | 0.47 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.47 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140044 | 0.92 | MTOR (0.54) | MTORRPTORMLST8ALDH1A1NPSR1 | |
| SCHEMBL20157119 | 0.89 | MTOR (0.42) | LMNAMTORRPTORMLST8EED | |
| SCHEMBL20140884 | 0.88 | MTOR (0.51) | LMNAMTORRPTORMLST8EED | |
| SCHEMBL20156931 | 0.87 | MTOR (0.51) | MTORRPTORMLST8ALDH1A1NPSR1 | |
| SCHEMBL20140587 | 0.84 | MTOR (0.54) | LMNAMTORRPTORMLST8ALDH1A1 | |
| SCHEMBL20140693 | 0.84 | HCRTR1 (0.49) | MTORRPTORMLST8ALDH1A1NPSR1 | |
| SCHEMBL20140600 | 0.83 | KDM4E (0.54) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20139930 | 0.83 | MTOR (0.53) | LMNAMTORRPTORMLST8ALDH1A1 | |
| SCHEMBL20140716 | 0.83 | MTOR (0.53) | MTORRPTORMLST8ALDH1A1NPSR1 | |
| SCHEMBL20157539 | 0.82 | MTOR (0.46) | LMNAMTORRPTORMLST8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |