Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139955 | 0.85 | KDM4E (0.52) | HTR7KDM4EALDH1A1NPSR1ATM | |
| SCHEMBL20140098 | 0.83 | ALDH1A1 (0.56) | HTR7KDM4EALDH1A1ATMDRD2 | |
| SCHEMBL20140640 | 0.81 | KDM4E (0.56) | HTR7KDM4EALDH1A1NPSR1ATM | |
| SCHEMBL20156931 | 0.81 | MTOR (0.51) | HTR7KDM4EALDH1A1NPSR1DRD2 | |
| SCHEMBL20142392 | 0.81 | P2RX7 (0.51) | HTR7ATM | |
| SCHEMBL20140759 | 0.79 | KDM4E (0.56) | HTR7KDM4EALDH1A1ATMDRD2 | |
| SCHEMBL3243301 | 0.79 | LMNA (0.60) | KDM4EALDH1A1NPSR1ATMDRD2 | |
| SCHEMBL20141481 | 0.77 | KDM4E (0.51) | HTR7KDM4EALDH1A1NPSR1ATM | |
| SCHEMBL6864941 | 0.77 | DRD4 (0.81) | HTR7KDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL4527775 | 0.76 | DRD4 (0.57) | HTR7ALDH1A1NPSR1ATMDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |