Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18411537 | 0.82 | PDK2 (0.46) | PDK2ALDH1A1MAPTNPC1TP53 | |
| SCHEMBL3892797 | 0.80 | ALDH1A1 (0.49) | PDK2ARALDH1A1MAPTNPC1 | |
| SCHEMBL2933216 | 0.78 | LMNA (0.51) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL28168702 | 0.76 | LMNA (0.54) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL27009920 | 0.73 | TERT (0.44) | PDK2ALDH1A1MAPTNPC1TP53 | |
| SCHEMBL22289269 | 0.73 | ALDH1A1 (0.61) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL19998610 | 0.73 | HPGD (0.47) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL17514156 | 0.73 | ADRB1 (0.47) | ALDH1A1MAPTNPC1TP53RAB9A | |
| SCHEMBL10899967 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12721277 | 0.72 | LTA4H (0.44) | ARALDH1A1MAPTNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538522-A1 | ROR GAMMA MODULATORS | Bristol-Myers Squibb Company (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |