Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140759 | 0.92 | KDM4E (0.56) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL20141745 | 0.84 | DRD4 (0.49) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL20140202 | 0.81 | HTR7 (0.55) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL6865213 | 0.79 | ALDH1A1 (0.67) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL20140902 | 0.78 | HTR7 (0.48) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL18177899 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL2454168 | 0.78 | DRD4 (0.63) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL6029899 | 0.77 | SIGMAR1 (0.68) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL6864941 | 0.77 | DRD4 (0.81) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL7108073 | 0.76 | DRD2 (0.58) | DRD2DRD4DRD3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |