Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.43 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156887 | 0.90 | PPARG (0.46) | PPARARETKDM4EALDH1A1HTT | |
| SCHEMBL20140585 | 0.89 | PPARG (0.47) | PPARARETMTORRPTORMLST8 | |
| SCHEMBL20139934 | 0.89 | PPARG (0.47) | RETKDM4EALDH1A1HTTPRKAA2 | |
| SCHEMBL20140044 | 0.86 | MTOR (0.54) | KDM4EALDH1A1HTTNPSR1MTOR | |
| SCHEMBL20141182 | 0.82 | PARP1 (0.48) | KDM4EALDH1A1GAAHTTCLK1 | |
| SCHEMBL20156931 | 0.82 | MTOR (0.51) | KDM4EALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL20156930 | 0.82 | MTOR (0.46) | KDM4EALDH1A1NPSR1MTORRPTOR | |
| SCHEMBL20140785 | 0.82 | PARP1 (0.47) | KDM4EALDH1A1HTTNPSR1MTOR | |
| SCHEMBL20140600 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1MTORRPTORMLST8 | |
| SCHEMBL20157329 | 0.81 | PPARA (0.49) | PPARAKDM4EALDH1A1L3MBTL1PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |