Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | SORD | Q00796 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21360407 | 0.82 | GPR119 (0.56) | GPR119 | |
| SCHEMBL20141307 | 0.82 | GRM1 (0.46) | SLC6A7KDM4EKMT2AGRM1 | |
| SCHEMBL26915035 | 0.80 | CHRM2 (0.40) | — | |
| SCHEMBL29274283 | 0.80 | CHRM2 (0.40) | — | |
| SCHEMBL20141438 | 0.78 | MTOR (0.45) | SLC6A7DPP4DPP8DPP9 | |
| SCHEMBL20141319 | 0.75 | LMNA (0.45) | KMT2A | |
| SCHEMBL16653814 | 0.75 | CHRM4 (0.41) | SLC6A7 | |
| SCHEMBL3710705 | 0.72 | SLC6A7 (0.62) | SLC6A7KDM4EKMT2AGPR119SORD | |
| SCHEMBL19124843 | 0.72 | ADAMTS5 (0.34) | — | |
| SCHEMBL27233767 | 0.72 | CHRM4 (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |