Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20270701 | 0.82 | IMPDH2 (0.35) | IMPDH2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL23064180 | 0.82 | KDM1A (0.35) | IMPDH2ALDH1A1 | |
| SCHEMBL6064223 | 0.82 | PGK1 (0.37) | PGK1PGK2ALDH1A1 | |
| SCHEMBL15308626 | 0.82 | NPSR1 (0.39) | PGK1PGK2ALDH1A1 | |
| SCHEMBL26601688 | 0.79 | — | — | |
| SCHEMBL14742524 | 0.79 | ALOX12 (0.35) | IMPDH2POLBL3MBTL1ALDH1A1 | |
| SCHEMBL5014656 | 0.78 | NOS3 (0.39) | PGK1PGK2POLBL3MBTL1BCHE | |
| SCHEMBL16011566 | 0.73 | FFAR4 (0.36) | POLBL3MBTL1ALDH1A1 | |
| SCHEMBL2223090 | 0.73 | PYCR1 (0.44) | POLBALDH1A1 | |
| SCHEMBL20141110 | 0.73 | POLB (0.35) | PGK1PGK2POLBL3MBTL1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |