Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.46 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140767 | 0.86 | MTOR (0.54) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20159215 | 0.86 | MTOR (0.61) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20139946 | 0.83 | MTOR (0.48) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20140751 | 0.79 | MTOR (0.60) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20140812 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL20140023 | 0.79 | MTOR (0.61) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20139966 | 0.79 | MTOR (0.61) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20140531 | 0.78 | MTOR (0.49) | MTORRPTORMLST8ALDH1A1GAA | |
| SCHEMBL20159231 | 0.76 | MTOR (0.68) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20157035 | 0.75 | NPC1 (0.46) | MTORRPTORMLST8ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |