Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GOT1 | P17174 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | PTPRE | P23469 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140820 | 0.81 | LMNA (0.43) | ALDH1A1LMNAMAPT | |
| SCHEMBL20141173 | 0.80 | MEN1 (0.34) | KEAP1GHSRBCHELMNAGOT1 | |
| SCHEMBL26683753 | 0.75 | DRD2 (0.47) | ALDH1A1LMNADRD2DRD4DRD3 | |
| SCHEMBL20141537 | 0.74 | KEAP1 (0.47) | KEAP1BCHEALDH1A1MAPTGOT1 | |
| SCHEMBL1225685 | 0.70 | ALDH1A1 (0.51) | GHSRALDH1A1LMNAMAPTGAA | |
| SCHEMBL26119201 | 0.69 | MAPK14 (0.40) | ALDH1A1LMNADRD2DRD4DRD3 | |
| SCHEMBL3723654 | 0.69 | KIT (0.46) | ALDH1A1AURKAJAK3 | |
| SCHEMBL6097862 | 0.69 | KEAP1 (0.41) | KEAP1GHSRBCHEALDH1A1PTPRC | |
| SCHEMBL3721191 | 0.66 | MAPK14 (0.46) | GHSRALDH1A1MAPTGAAKDM4E | |
| SCHEMBL23777655 | 0.64 | NOTUM (0.54) | ALDH1A1LMNAMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |