SCHEMBL20142742

SCHEMBL20142742

O=C(Cn1nc(C(F)(F)F)c2c1CCCC2)N1CCCc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNJ2 P63252 1/20 1.00
ALOX15 P16050 2/20 0.57
LMNA P02545 4/20 0.56
POLQ O75417 1/20 0.55
TSHR P16473 2/20 0.55
GAA P10253 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
POLB P06746 4/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 1/20 0.53
PKM P14618 1/20 0.53
TP53 P04637 2/20 0.51
MAPT P10636 1/20 0.51
HSD17B10 Q99714 1/20 0.51
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30367110 1.00 KCNJ2 (1.00) KCNJ2ALOX15LMNAPOLQTSHR
SCHEMBL1006785 0.95 KCNJ2 (0.90) KCNJ2ALOX15LMNAPOLQTSHR
SCHEMBL15485012 0.79 KCNJ2 (0.65) KCNJ2ALOX15LMNAPOLQTSHR
SCHEMBL15484885 0.77 KCNJ2 (0.62) KCNJ2ALOX15LMNATSHRGAA
SCHEMBL1893079 0.73 TP53 (0.74) LMNATSHRGAAPOLBTP53
SCHEMBL1008435 0.73 LMNA (1.00) LMNAPOLQTSHRGAANPSR1
SCHEMBL20371480 0.72 LMNA (1.00) LMNAPOLQTSHRGAANPSR1
SCHEMBL15708803 0.72 LMNA (1.00) LMNAPOLQTSHRGAANPSR1
SCHEMBL12379943 0.72 LMNA (0.76) LMNAPOLQTSHRGAANPSR1
SCHEMBL29538698 0.71 ALDH1A1 (0.84) ALOX15GAAPOLBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12295368-B2 Method for controlling hematophagous or sap-feeding arthropods BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSTIY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2025-05-13 US disclosed
US-20230276802-A1 Method for Controlling Hematophagous or Sap-Feeding Arthropods BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSTIY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2023-09-07 US disclosed
US-11632953-B2 Method for controlling hematophagous or sap-feeding arthropods BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2023-04-25 US disclosed
US-20190320655-A1 Method for Controlling Hematophagous or Sap-Feeding Arthropods BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2019-10-24 US disclosed
EP-3537880-A1 METHOD FOR CONTROLLING HEMATOPHAGOUS OR SAP-FEEDING ARTHROPODS Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) 2019-09-18 EP disclosed
WO-2018089874-A1 METHOD FOR CONTROLLING HEMATOPHAGOUS OR SAP-FEEDING ARTHROPODS BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2018-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11632953-B2 Method for controlling hematophagous or sap-feeding arthropods KCNN1, KCNN2, KCNN3 KCNJ2 15/4885ALOX15 4353/4885LMNA 4713/4885
US-12295368-B2 Method for controlling hematophagous or sap-feeding arthropods KCNN1, KCNN2, KCNN3 KCNJ2 15/4885ALOX15 4353/4885LMNA 4713/4885
US-20190320655-A1 Method for Controlling Hematophagous or Sap-Feeding Arthropods KCNN1, KCNN2, KCNN3 KCNJ2 15/4885ALOX15 4353/4885LMNA 4713/4885
US-20230276802-A1 Method for Controlling Hematophagous or Sap-Feeding Arthropods KCNN1, KCNN2, KCNN3 KCNJ2 15/4885ALOX15 4353/4885LMNA 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.