SCHEMBL201430

SCHEMBL201430

CCCC[Sn](CCCC)(CCCC)c1nccn1C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
TLR8 Q9NR97 2/20 0.41
LPO P22079 1/20 0.38
HTT P42858 1/20 0.35
FDPS P14324 1/20 0.33
CYP19A1 P11511 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TBXAS1 P24557 1/20 0.32
TLR7 Q9NYK1 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15531306 0.78 TLR8 (0.42) KMT2AALDH1A1POLBTLR8LPO
SCHEMBL18038297 0.75 KMT2A (0.42) KMT2AALDH1A1POLBTLR8CYP19A1
SCHEMBL6767037 0.74 ALDH1A1 (0.45) KMT2AALDH1A1POLBTLR8CYP1A2
SCHEMBL3065697 0.73 ALDH1A1 (0.40) KMT2AALDH1A1POLBTLR8CYP19A1
SCHEMBL3171671 0.72 CYP1A2 (0.32) KMT2AALDH1A1POLBCYP19A1CYP1A2
SCHEMBL18038278 0.71 ALDH1A1 (0.32) KMT2AALDH1A1POLBTLR8CYP19A1
SCHEMBL7972375 0.71 KDM4E (0.33) KMT2AALDH1A1POLBTLR8HTT
SCHEMBL6767033 0.71 ALDH1A1 (0.32) KMT2AALDH1A1POLBTLR8
SCHEMBL18007731 0.70 KMT2A (0.35) KMT2AALDH1A1POLBHTTMEN1
Pentane SCHEMBL19922685 0.69 ALDH1A1 (0.62) KMT2AALDH1A1POLBTLR8LPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4735114-A1 SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES Masarykova Univerzita (CZ) 2026-05-06 EP disclosed
EP-4142732-B1 METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS GLOBAL BLOOD THERAPEUTICS INC (US) 2026-04-22 EP disclosed
US-12509451-B2 Heteroaryl amide inhibitors of CD38 NAPA THERAPEUTICS LIMITED (IM) 2025-12-30 US disclosed
US-12503468-B2 Heterocyclic compound, intermediate, preparation method therefor and application thereof WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2025-12-23 US disclosed
EP-4007752-B1 KIF18A INHIBITORS AMGEN INC (US) 2025-09-24 EP disclosed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
US-20250109122-A1 CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS GLOBAL BLOOD THERAPEUTICS INC (US) 2025-04-03 US disclosed
US-12202817-B2 Cycloalkyl pyrimidines as ferroportin inhibitors GLOBAL BLOOD THERAPEUTICS, INC. (US) 2025-01-21 US disclosed
WO-2025002491-A1 SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES MASARYKOVA UNIVERZITA (CZ) 2025-01-02 WO disclosed
US-20240417388-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-12-19 US disclosed
EP-0934311-A2 NEW HETEROCYCLYLMETHYL-SUBSTITUTED PYRAZOL DERIVATES BAYER AG (DE) 1999-08-11 EP disclosed
EP-0912559-A1 FUSED HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 1999-05-06 EP disclosed
EP-0850924-A1 Aromatic diselenides and selenosulphides for use as antioxidant agents OXIS Isle of Man, Limited (GB) 1998-07-01 EP disclosed
WO-1998016507-A2 NEW HETEROCYCLYLMETHYL-SUBSTITUTED PYRAZOL DERIVATES AND THEIR USE FOR TREATING CARDIOVASCULAR DISEASES BAYER AKTIENGESELLSCHAFT (DE) 1998-04-23 WO disclosed
WO-1998002434-A1 FUSED HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 1998-01-22 WO disclosed
US-5656754-A REACTING AN ALLENYL-B-LACTAM COMPOUND WITH AN ORGANOTIN COMPOUND OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-08-12 US disclosed
EP-0623622-A1 PROCESS FOR PRODUCING CEPHEM COMPOUND OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1994-11-09 EP disclosed
EP-0343277-B1 A process for the production of 3-hydrocarbyl-3-cephems BRISTOL MYERS SQUIBB CO (US) 1994-10-05 EP disclosed
EP-0343277-A1 A process for the production of 3-hydrocarbyl-3-cephems Bristol-Myers Squibb Company (US) 1989-11-29 EP disclosed
US-4857539-A Heterocyclic substituted-phenoxyalkylisoxazoles as antiviral useful agents STERLING DRUG INC. (US) 1989-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12202817-B2 Cycloalkyl pyrimidines as ferroportin inhibitors HAMP, SLC40A1, FANCI KMT2A 4677/4885ALDH1A1 1674/4885POLB 480/4885
US-20240417388-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 BCL6, BCL6B, BCL3 KMT2A 752/4885ALDH1A1 1654/4885POLB 3001/4885
US-12503468-B2 Heterocyclic compound, intermediate, preparation method therefor and application thereof P2RX3, P2RX7, P2RX4 KMT2A 4633/4885ALDH1A1 996/4885POLB 4161/4885
US-12509451-B2 Heteroaryl amide inhibitors of CD38 CD38, FCGRT, BCL6 KMT2A 1927/4885ALDH1A1 215/4885POLB 3365/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 KMT2A 1011/4885ALDH1A1 800/4885POLB 364/4885
US-20250109122-A1 CYCLOALKYL PYRIMIDINES AS FERROPORTIN INHIBITORS HAMP, SLC40A1, FANCI KMT2A 4677/4885ALDH1A1 1674/4885POLB 480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.