Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 13/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20145104 | 0.87 | KMT2A (0.46) | IL1BNLRP3HCRTR1SSTR4PTK2 | |
| SCHEMBL20145073 | 0.81 | IL1B (0.50) | IL1BNLRP3HCRTR1 | |
| SCHEMBL20144818 | 0.81 | IL1B (0.50) | IL1BNLRP3HCRTR1 | |
| SCHEMBL20144750 | 0.78 | IL1B (0.55) | IL1BNLRP3HCRTR1 | |
| SCHEMBL20145221 | 0.78 | IL1B (0.55) | IL1BNLRP3HCRTR1 | |
| SCHEMBL26151633 | 0.77 | ACACB (0.35) | HCRTR1ACACBSSTR4 | |
| SCHEMBL26151636 | 0.73 | ACACB (0.39) | HCRTR1ACACB | |
| SCHEMBL20144776 | 0.73 | IL1B (0.53) | IL1BNLRP3HCRTR1 | |
| SCHEMBL20144953 | 0.73 | HCRTR1 (0.70) | HCRTR1 | |
| SCHEMBL20145035 | 0.73 | HCRTR1 (0.70) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |