Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FABP2 | P12104 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459044 | 0.82 | CES2 (0.48) | MLYCDTRPM8GPBAR1LMNAACHE | |
| SCHEMBL27878097 | 0.77 | TTR (0.54) | MEN1KMT2APTGS1PTGS2FABP2 | |
| SCHEMBL13670738 | 0.75 | NPSR1 (0.62) | MLYCDTRPM8MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26709446 | 0.75 | LMNA (0.42) | MLYCDPTGS1PTGS2LMNATSHR | |
| SCHEMBL18069275 | 0.74 | OXTR (0.49) | MLYCDMEN1KMT2ASMN1; SMN2PTGS2 | |
| SCHEMBL8986031 | 0.74 | MEN1 (0.69) | TRPM8MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL23573107 | 0.74 | DHODH (0.49) | MEN1KMT2APTGS1PTGS2LMNA | |
| SCHEMBL4449884 | 0.74 | MAPT (0.56) | MLYCDSMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL20982579 | 0.73 | MLYCD (0.49) | MLYCDTRPM8KMT2ALMNAACHE | |
| SCHEMBL772236 | 0.73 | KMO (0.53) | MEN1KMT2ALMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |