Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 2/20 | 0.34 |
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035544 | 0.84 | GABRA1 (0.43) | SLC22A6SLC22A8GRM1HPGDALDH1A1 | |
| SCHEMBL31411955 | 0.73 | GLA (0.45) | GRM1HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28058314 | 0.72 | GPR52 (0.49) | ALDH1A1MAPT | |
| SCHEMBL4430320 | 0.71 | FOLH1 (0.59) | HMGB1HPGDALDH1A1KDM4EMAPT | |
| SCHEMBL28844937 | 0.71 | KDM4E (0.37) | SLC22A6SLC22A8ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8895803 | 0.71 | KDM4E (0.43) | SLC22A6SLC22A8KDM4EHSD17B10 | |
| Hydrogen Sulfide SCHEMBL27554346 | 0.70 | L3MBTL1 (0.43) | ALDH1A1KDM4EHSD17B10MYCL3MBTL1 | |
| SCHEMBL14303113 | 0.70 | HMGB1 (0.45) | HMGB1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14092931 | 0.70 | AKR1C3 (0.44) | KDM4EHSD17B10PTPN1 | |
| SCHEMBL8772614 | 0.69 | SLC22A6 (0.44) | SLC22A6SLC22A8HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970106-B1 | BORON-CONTAINING DIACYLHYDRAZINES | INTREXON CORP (US) | 2018-05-16 | — | — | EP | disclosed |