Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148931 | 0.82 | SIGMAR1 (0.55) | SIGMAR1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11972180 | 0.81 | TRPV3 (0.56) | SIGMAR1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL22574694 | 0.81 | TRPV3 (0.56) | SIGMAR1POLBALDH1A1MAPTMEN1 | |
| SCHEMBL1515577 | 0.81 | SIGMAR1 (0.53) | SIGMAR1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11971879 | 0.81 | SIGMAR1 (0.53) | SIGMAR1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11972186 | 0.81 | TRPV3 (0.56) | SIGMAR1POLBALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11133532 | 0.81 | SIGMAR1 (0.53) | SIGMAR1POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13995225 | 0.80 | SIGMAR1 (0.74) | SIGMAR1POLBALDH1A1CYP3A4 | |
| SCHEMBL13995594 | 0.80 | SIGMAR1 (0.74) | SIGMAR1POLBALDH1A1CYP3A4 | |
| SCHEMBL13995584 | 0.80 | SIGMAR1 (0.74) | SIGMAR1POLBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905711-B2 | Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal | VIFOR (INTERNATIONAL) LTD. (CH) | 2021-02-02 | — | — | US | disclosed |
| US-20180133244-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL | VIFOR (INTERNATIONAL) LTD. (CH) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905711-B2 | Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal | KCNN3, KCNH3, KCNH2 | SIGMAR1 3498/4885POLB 3987/4885PSMB5 1046/4885 |
| US-20180133244-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL | KCNN3, KCNH3, KCNH2 | SIGMAR1 3498/4885POLB 3987/4885PSMB5 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.