Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11133532 | 0.98 | SIGMAR1 (0.53) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL31049620 | 0.85 | SIGMAR1 (0.52) | SIGMAR1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL15818086 | 0.85 | SIGMAR1 (0.52) | SIGMAR1POLBMAPTSMN1; SMN2MEN1 | |
| SCHEMBL172382 | 0.83 | SIGMAR1 (0.50) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL1515577 | 0.82 | SIGMAR1 (0.53) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL11972180 | 0.82 | TRPV3 (0.56) | SIGMAR1POLBMAPTMEN1KMT2A | |
| SCHEMBL11971879 | 0.82 | SIGMAR1 (0.53) | SIGMAR1POLBKDM4ECYP3A4MAPT | |
| SCHEMBL22574694 | 0.82 | TRPV3 (0.56) | SIGMAR1POLBMAPTMEN1KMT2A | |
| SCHEMBL11972186 | 0.82 | TRPV3 (0.56) | SIGMAR1POLBMAPTMEN1KMT2A | |
| SCHEMBL20148924 | 0.82 | SIGMAR1 (0.53) | SIGMAR1POLBKDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10905711-B2 | Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal | VIFOR (INTERNATIONAL) LTD. (CH) | 2021-02-02 | — | — | US | disclosed |
| US-20180133244-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL | VIFOR (INTERNATIONAL) LTD. (CH) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10905711-B2 | Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal | KCNN3, KCNH3, KCNH2 | SIGMAR1 3498/4885POLB 3987/4885KDM4E 1404/4885 |
| US-20180133244-A1 | METHODS AND COMPOSITIONS FOR SELECTIVELY REMOVING POTASSIUM ION FROM THE GASTROINTESTINAL TRACT OF A MAMMAL | KCNN3, KCNH3, KCNH2 | SIGMAR1 3498/4885POLB 3987/4885KDM4E 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.