Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148977 | 0.79 | RORC (0.46) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL8021367 | 0.77 | NR1H2 (0.58) | RORCNR1I2RORANR1H2NR1H3 | |
| SCHEMBL20148982 | 0.77 | RORC (0.50) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL20149268 | 0.77 | RORC (0.50) | RORCNR1I2 | |
| SCHEMBL20140451 | 0.74 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL20140250 | 0.74 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL15467792 | 0.69 | RORC (0.40) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL131990 | 0.69 | NR1H2 (0.68) | NR1H2NR1H3 | |
| SCHEMBL20149260 | 0.67 | RORC (0.54) | RORCNR1I2NR1H2NR1H3 | |
| Water SCHEMBL1684070 | 0.66 | NR1H2 (0.65) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |