Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149268 | 0.81 | RORC (0.50) | RORCNR1I2 | |
| SCHEMBL20148977 | 0.78 | RORC (0.46) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL20149019 | 0.77 | RORC (0.57) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL8021367 | 0.76 | NR1H2 (0.58) | RORCNR1I2NR1H2NR1H3 | |
| SCHEMBL20149050 | 0.74 | RORC (0.84) | RORCNR1I2 | |
| SCHEMBL20149047 | 0.71 | RORC (0.90) | RORCNR1I2 | |
| SCHEMBL16109604 | 0.70 | KDM1A (0.57) | — | |
| SCHEMBL16133827 | 0.70 | KDM1A (0.57) | — | |
| SCHEMBL8782674 | 0.70 | SLC6A2 (0.42) | — | |
| SCHEMBL9137150 | 0.70 | SLC6A2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089406-A1 | ROR GAMMA MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |