SCHEMBL20149266

SCHEMBL20149266

CC(C)S(=O)(=O)c1ccc(N)cc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.43
FEN1 P39748 4/20 0.39
ALOX5AP P20292 3/20 0.39
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
CNR1 P21554 1/20 0.36
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD11B1 P28845 1/20 0.33
C1S P09871 1/20 0.33
PTPRC P08575 2/20 0.32
LMNA P02545 2/20 0.32
POLB P06746 2/20 0.32
MEN1 O00255 1/20 0.32
APAF1 O14727 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12325549 0.85 ALOX5AP (0.42) L3MBTL1FEN1ALOX5APNPC1RAB9A
SCHEMBL9963191 0.81 POLB (0.45) NPC1RAB9AALDH1A1TDP1LMNA
SCHEMBL239424 0.79 L3MBTL1 (0.62) L3MBTL1FEN1ALOX5APALDH1A1CYP3A4
SCHEMBL29377271 0.79 L3MBTL1 (0.62) L3MBTL1FEN1ALOX5APALDH1A1CYP3A4
SCHEMBL14443238 0.78 CCR2 (0.50) L3MBTL1CNR1ALDH1A1MAPK1LMNA
SCHEMBL12682798 0.78 L3MBTL1 (0.43) L3MBTL1NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL31618994 0.76 L3MBTL1 (0.44) L3MBTL1ALDH1A1TP53CYP3A4TSHR
SCHEMBL1575759 0.76 CA2 (0.44) L3MBTL1NPC1RAB9AALDH1A1CYP3A4
SCHEMBL31618993 0.76 L3MBTL1 (0.44) L3MBTL1ALDH1A1TP53CYP3A4TSHR
SCHEMBL30049401 0.76 CA2 (0.44) L3MBTL1NPC1RAB9AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 US disclosed
US-20180155389-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2018-06-07 US disclosed
WO-2018089373-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2018-05-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180155389-A1 STEROIDS AND PROTEIN-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 L3MBTL1 2840/4885FEN1 3247/4885ALOX5AP 3138/4885
US-11760775-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 L3MBTL1 2855/4885FEN1 3323/4885ALOX5AP 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.