SCHEMBL20149464

SCHEMBL20149464

c1ccc2c(c1)cc(-n1c3ccccc3c3ccc(-c4cccc5c6ccccc6n(-c6cc7ccccc7c7ccccc67)c45)cc31)c1ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
DUSP3 P51452 1/20 0.38
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP11B1 P15538 1/20 0.33
TUBB4A P04350 1/20 0.33
TUBB P07437 1/20 0.33
TUBA3C P0DPH7 1/20 0.33
TUBA1B P68363 1/20 0.33
TUBA4A P68366 1/20 0.33
TUBB4B P68371 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20149453 0.94 L3MBTL1 (0.40) CYP1A2CYP2C9CYP2C19DUSP3TDP1
SCHEMBL20149451 0.92 L3MBTL1 (0.44) CYP1A2CYP2C9CYP2C19DUSP3TDP1
SCHEMBL25972721 0.89 CYP1A2 (0.38) CYP1A2CYP2C9CYP2C19TDP1ALDH1A1
SCHEMBL20149429 0.87 CYP1A2 (0.45) CYP1A2CYP2C9CYP2C19TDP1ALDH1A1
SCHEMBL20149457 0.87 DUSP3 (0.44) CYP1A2CYP2C9CYP2C19DUSP3TDP1
SCHEMBL20149472 0.86 L3MBTL1 (0.40) CYP1A2CYP2C9CYP2C19DUSP3TDP1
SCHEMBL20149440 0.86 DUSP3 (0.40) DUSP3TDP1ALDH1A1L3MBTL1HPGD
SCHEMBL20706789 0.85 L3MBTL1 (0.44) CYP1A2CYP2C9CYP2C19DUSP3TDP1
SCHEMBL780867 0.84 ALOX5 (0.37) CYP1A2CYP2C9CYP2C19TDP1ALDH1A1
SCHEMBL20149473 0.83 CYP1A2 (0.42) CYP1A2CYP2C9CYP2C19TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230139757-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230023388-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20220173326-A1 MELT MIXTURE FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-02 US disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138420-A1 ORGANIC ELECTROLUMINESCENT ELEMENT EML4, LAGE3, KCNN4 CYP1A2 613/4885CYP2C9 521/4885CYP2C19 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.