Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2341786 | 0.79 | HTR2A (0.44) | DRD4DRD2 | |
| SCHEMBL20149778 | 0.79 | DRD4 (0.43) | KDM1ACHRM4DRD4DRD2NPY2R | |
| SCHEMBL7714987 | 0.76 | KDM4E (0.44) | KDM1ACHRM4DRD4DRD2C5AR1 | |
| SCHEMBL7967422 | 0.76 | NPY2R (0.46) | KDM1ACHRM4DRD4DRD2ADAM17 | |
| SCHEMBL233169 | 0.74 | ADRB1 (0.58) | DRD2 | |
| SCHEMBL7520833 | 0.74 | CHRM4 (0.49) | CHRM4DRD4DRD2ADAM17C5AR1 | |
| SCHEMBL20149928 | 0.74 | KDM4E (0.44) | KDM1ACHRM4DRD4DRD2 | |
| SCHEMBL7715922 | 0.73 | DRD4 (0.47) | CHRM4DRD4DRD2 | |
| Hydrochloric Acid SCHEMBL29882725 | 0.73 | ADRB1 (0.56) | DRD2 | |
| Hydrochloric Acid SCHEMBL20139829 | 0.73 | ADRB1 (0.56) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214832-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-04-10 | — | — | US | disclosed |