Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.36 |
| ▸ | CLK1 | P49759 | 5/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011451 | 0.78 | NUDT1 (0.42) | NUDT1L3MBTL1BCL6CHUK | |
| SCHEMBL2745753 | 0.77 | NUDT1 (0.58) | NUDT1BCL6 | |
| SCHEMBL18567341 | 0.77 | CYP1A2 (0.30) | — | |
| SCHEMBL2744648 | 0.75 | BCL6 (0.56) | NUDT1L3MBTL1BCL6CDK5CHUK | |
| SCHEMBL14994344 | 0.75 | BCL6 (0.56) | NUDT1BCL6 | |
| SCHEMBL20150284 | 0.75 | JAK1 (0.46) | NUDT1L3MBTL1BCL6CHUK | |
| SCHEMBL3644211 | 0.75 | XDH (0.41) | L3MBTL1 | |
| SCHEMBL2745948 | 0.73 | DHFR (0.43) | NUDT1 | |
| SCHEMBL20434305 | 0.73 | L3MBTL1 (0.63) | L3MBTL1 | |
| SCHEMBL5763052 | 0.72 | NUDT1 (0.38) | NUDT1L3MBTL1BCL6CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3530657-A1 | 2-POLYSUBSTITUTED AROMATIC RING-PYRIMIDINE DERIVATIVE AND PREPARATION AND MEDICAL USE | Zhejiang University (CN) | 2019-08-28 | — | — | EP | disclosed |
| WO-2018086546-A1 | 2-POLYSUBSTITUTED AROMATIC RING-PYRIMIDINE DERIVATIVE AND PREPARATION AND MEDICAL USE | 浙江大学 | 2018-05-17 | — | — | WO | disclosed |