SCHEMBL20152508

SCHEMBL20152508

CC(C)c1ccc2c(c1)Oc1ccccc1N2c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 6/20 0.39
MIF P14174 1/20 0.37
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
KIF11 P52732 1/20 0.34
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
TP53 P04637 1/20 0.34
MGLL Q99685 1/20 0.33
NR1H3 Q13133 1/20 0.33
CDK8 P49336 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102475 0.91 P2RX4 (0.39) P2RX4MIFMAPTSMN1; SMN2NPSR1
SCHEMBL15458030 0.88 MIF (0.36) MIFSMN1; SMN2NPSR1EGLN1KIF11
SCHEMBL20160867 0.88 P2RX4 (0.37) P2RX4MAPTSMN1; SMN2NPSR1CDK8
SCHEMBL13706095 0.85 MGLL (0.46) P2RX4MGLL
SCHEMBL20935976 0.84 P2RX4 (0.41) P2RX4MAPTSMN1; SMN2NPSR1ALDH1A1
SCHEMBL17278485 0.82 MAPT (0.39) MIFMAPTSMN1; SMN2EGLN1LMNA
SCHEMBL1102443 0.80 MGLL (0.39) MIFMAPTSMN1; SMN2NPSR1EGLN1
SCHEMBL29379993 0.80 P2RX4 (0.47) P2RX4NPSR1ALDH1A1MGLL
SCHEMBL29406608 0.80 P2RX4 (0.47) P2RX4NPSR1ALDH1A1MGLL
SCHEMBL1573992 0.80 P2RX4 (0.47) P2RX4NPSR1ALDH1A1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11638390-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-04-25 US disclosed
US-20200119287-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2020-04-16 US disclosed
US-10580996-B2 Polycyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-03-03 US disclosed
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-31 US disclosed
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200119287-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, CLTB, CYBA P2RX4 1164/4885MIF 462/4885MAPT 102/4885
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY2, NR2E3, CRY1 P2RX4 1277/4885MIF 3838/4885MAPT 530/4885
US-20180148640-A1 DOUBLE SPIRO ORGANIC COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME DCX, TERT, TELO2 P2RX4 3135/4885MIF 2682/4885MAPT 1276/4885
US-10580996-B2 Polycyclic compound and organic light-emitting element comprising same CRY2, NR2E3, CRY1 P2RX4 1277/4885MIF 3838/4885MAPT 530/4885
US-11638390-B2 Composition of matter for use in organic light-emitting diodes CRY2, CLTB, CYBA P2RX4 1164/4885MIF 462/4885MAPT 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.