SCHEMBL1102443

SCHEMBL1102443

CC(C)c1ccc2c(c1)N(c1ccccc1)c1ccccc1N2c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.39
ALDH1A1 P00352 4/20 0.38
LMNA P02545 3/20 0.38
TSHR P16473 1/20 0.38
NR1H3 Q13133 1/20 0.38
NOTUM Q6P988 2/20 0.36
MIF P14174 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
KIF11 P52732 1/20 0.36
NPSR1 Q6W5P4 3/20 0.35
RECQL P46063 1/20 0.35
MAPT P10636 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
OPRK1 P41145 1/20 0.35
PDE4D Q08499 1/20 0.35
CES2 O00748 1/20 0.34
BCHE P06276 1/20 0.34
GAA P10253 1/20 0.34
CES1 P23141 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1102509 0.93 NR1H3 (0.40) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL13338349 0.83 ALDH1A1 (0.41) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL1102474 0.82 MGLL (0.38) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL30055977 0.81 GNG2 (0.49) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL28497458 0.81 GNG2 (0.49) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL1102514 0.80 HPGD (0.49) MGLLALDH1A1LMNATSHRNOTUM
SCHEMBL1102427 0.80 MIF (0.35) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL1102472 0.80 HPGD (0.41) ALDH1A1LMNATSHRNOTUMEGLN1
SCHEMBL1102475 0.80 P2RX4 (0.39) MGLLALDH1A1LMNATSHRMIF
SCHEMBL1102436 0.80 BCHE (0.42) ALDH1A1LMNANPSR1MAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235315-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 MGLL 1347/4885ALDH1A1 208/4885LMNA 3666/4885
US-20200235315-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TRPA1, PIEZO1, SLCO4C1 MGLL 1461/4885ALDH1A1 1276/4885LMNA 1366/4885
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OXER1, L1CAM, RPL41 MGLL 2571/4885ALDH1A1 1198/4885LMNA 1529/4885
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A MGLL 4337/4885ALDH1A1 1477/4885LMNA 4186/4885
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 MGLL 2682/4885ALDH1A1 428/4885LMNA 4085/4885
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 MGLL 1501/4885ALDH1A1 1015/4885LMNA 2738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.