Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | C1R | P00736 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29848512 | 0.81 | ALDH1A1 (0.71) | CASP6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL589016 | 0.81 | CASP6 (0.66) | CASP6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL28058443 | 0.81 | CASP6 (0.66) | CASP6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL30443747 | 0.81 | ALDH1A1 (0.71) | CASP6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL31725 | 0.81 | ALDH1A1 (0.71) | CASP6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL25783900 | 0.81 | GPR35 (0.65) | CASP6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL16582329 | 0.80 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL9162290 | 0.80 | CASP6 (0.65) | CASP6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL15821069 | 0.80 | HPRT1 (0.65) | CASP6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL17841980 | 0.80 | HPRT1 (0.65) | CASP6ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180138421-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180138421-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | CRY2, NR2E3, CRY1 | CASP6 2004/4885ALDH1A1 928/4885KMT2A 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.